Apparatus for analyzing the process of formation of aggregates in a biological fluid, such as blood or hematic fluids, comprising a perfusion chamber (11) provided with at least one micro-channel (33) through which the biological fluid flows, and in which at least one reactive substrate is present, such as a cyto- adhesive substrate, to stimulate the aggregation process in the biological fluid, and impedenziometric detection means (35) associated with the micro-channel (33), in correspondence to at least one investigation area (34) and disposed, during use, in contact with the flow of biological fluid in transit, in order to detect impedance data of the biological fluid. The impedenziometric detection means (35) comprise at least two first electrodes (36) with an oblong development disposed in the micro-channel (33), and a plurality of second electrodes (37) with an oblong development disposed in the space comprised between the first electrodes (36) and according to a pattern defining substantially the perimeter of a geometric figure.

Apparecchiatura per l'analisi del processo di formazione di aggregati in un fluido biologico e relativo metodo di analisi / Apparatus for analyzing the process of formation of aggregates in a biological fluid and corresponding method of analysis

AFFANNI, Antonio;SPECOGNA, Ruben;TREVISAN, Francesco
2015-01-01

Abstract

Apparatus for analyzing the process of formation of aggregates in a biological fluid, such as blood or hematic fluids, comprising a perfusion chamber (11) provided with at least one micro-channel (33) through which the biological fluid flows, and in which at least one reactive substrate is present, such as a cyto- adhesive substrate, to stimulate the aggregation process in the biological fluid, and impedenziometric detection means (35) associated with the micro-channel (33), in correspondence to at least one investigation area (34) and disposed, during use, in contact with the flow of biological fluid in transit, in order to detect impedance data of the biological fluid. The impedenziometric detection means (35) comprise at least two first electrodes (36) with an oblong development disposed in the micro-channel (33), and a plurality of second electrodes (37) with an oblong development disposed in the space comprised between the first electrodes (36) and according to a pattern defining substantially the perimeter of a geometric figure.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11390/867222
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