MALFATTI, MATILDE CLARISSA

MALFATTI, MATILDE CLARISSA  

DMED - DIPARTIMENTO DI MEDICINA  

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Abasic and oxidized ribonucleotides embedded in DNA are processed by human APE1 and not by RNase H2 1-gen-2017 Malfatti, MATILDE CLARISSA; Balachander, Sathya; Antoniali, Giulia; Koh, Kyung Duk; Saint pierre, Christine; Gasparutto, Didier; Chon, Hyongi; Crouch, Robert J; Storici, Francesca; Tell, Gianluca
APE1 and NPM1 protect cancer cells from platinum compounds cytotoxicity and their expression pattern has a prognostic value in TNBC 1-gen-2019 Malfatti, M. C.; Gerratana, L.; Dalla, E.; Isola, M.; Damante, G.; Di Loreto, C.; Puglisi, F.; Tell, G.
APE1 interacts with the nuclear exosome complex protein MTR4 and is involved in cisplatin- and 5-fluorouracil-induced RNA damage response 1-gen-2022 Codrich, M.; Degrassi, M.; Malfatti, M. C.; Antoniali, G.; Gorassini, A.; Ayyildiz, D.; Marco, De; Giancarlo, Verardo; Tell, Gianluca
AUF1 Recognizes 8-Oxo-Guanosine Embedded in DNA and Stimulates APE1 Endoribonuclease Activity 1-gen-2023 Malfatti, Mc; Codrich, M; Dalla, E; D'Ambrosio, C; Storici, F; Scaloni, A; Tell, G.
Combining Deep Phenotyping of Serum Proteomics and Clinical Data via Machine Learning for COVID-19 Biomarker Discovery 1-gen-2022 Beltrami, Antonio Paolo; De Martino, Maria; Dalla, Emiliano; Malfatti, Matilde Clarissa; Caponnetto, Federica; Codrich, Marta; Stefanizzi, Daniele; Fabris, Martina; Sozio, Emanuela; D'Aurizio, Federica; Pucillo, Carlo E M; Sechi, Leonardo A; Tascini, Carlo; Curcio, Francesco; Foresti, Gian Luca; Piciarelli, Claudio; De Nardin, Axel; Tell, Gianluca; Isola, Miriam
Coping with RNA damage with a focus on APE1, a BER enzyme at the crossroad between DNA damage repair and RNA processing/decay 1-gen-2021 Malfatti, M. C.; Antoniali, G.; Codrich, M.; Tell, G.
Emerging Concepts on the Early Steps of Base Excision Repair Pathway with a Focus on Gene Expression 1-gen-2020 Antoniali, G.; Malfatti, M. C.; Tell, G.
Enzymatically active apurinic/apyrimidinic endodeoxyribonuclease 1 is released by mammalian cells through exosomes 1-gen-2021 Mangiapane, G.; Parolini, I.; Conte, K.; Malfatti, M. C.; Corsi, J.; Sanchez, M.; Pietrantoni, A.; D'Agostino, V. G.; Tell, G.
Expression of APE1 endonuclease in primarily cultured aortic valve interstitial cells undergoing spontaneous senescence 1-gen-2023 Bonetti, Antonella; Antoniali, Giulia; Malfatti, MATILDE CLARISSA; Codrich, Marta; Contin, Magali; Tell, Gianluca; Ortolani, Fulvia
Human AP-endonuclease (Ape1) activity on telomeric G4 structures is modulated by acetylatable lysine residues in the N-terminal sequence 1-gen-2019 Burra, Silvia; Marasco, Daniela; Malfatti, Matilde Clarissa; Antoniali, Giulia; Virgilio, Antonella; Esposito, Veronica; Demple, Bruce; Galeone, Aldo; Tell, Gianluca
In Vitro Assay to Measure APE1 Enzymatic Activity on Ribose Monophosphate Abasic Site 1-gen-2023 Malfatti, M. C.; Antoniali, G.; Tell, G.
Inhibition of APE1-endonuclease activity affects cell metabolism in colon cancer cells via a p53-dependent pathway 1-gen-2019 Codrich, Marta; Comelli, Marina; Malfatti, Matilde Clarissa; Mio, Catia; Ayyildiz, Dilara; Zhang, Chi; Kelley, Mark R; Terrosu, Giovanni; Pucillo, Carlo E M; Tell, Gianluca
Inhibitors of the apurinic/apyrimidinic endonuclease 1 (APE1)/nucleophosmin (NPM1) interaction that display anti-tumor properties 1-gen-2015 Poletto, Mattia; Malfatti, MATILDE CLARISSA; Dorjsuren, Dorjbal; Scognamiglio, Pasqualina L; Marasco, Daniela; Vascotto, Carlo; Jadhav, Ajit; Maloney, David J; Wilson, David M; Simeonov, Anton; Tell, Gianluca
Integrated multi-omics analyses on patient-derived CRC organoids highlight altered molecular pathways in colorectal cancer progression involving PTEN 1-gen-2021 Codrich, M.; Dalla, E.; Mio, C.; Antoniali, G.; Malfatti, M. C.; Marzinotto, S.; Pierobon, M.; Baldelli, E.; Di Loreto, C.; Damante, G.; Terrosu, G.; Pucillo, C. E. M.; Tell, G.
New perspectives in cancer biology from a study of canonical and non-canonical functions of base excision repair proteins with a focus on early steps 1-gen-2020 Malfatti, M. C.; Antoniali, G.; Codrich, M.; Burra, S.; Mangiapane, G.; Dalla, E.; Tell, G.
Novel roles of DNA damage repair enzymes in the processing of modified ribonucleotides embedded in DNA 2-mar-2018 Malfatti, MATILDE CLARISSA
Platinum Salts in Patients with Breast Cancer: A Focus on Predictive Factors 1-gen-2019 Garutti, Mattia; Pelizzari, Giacomo; Bartoletti, Michele; Malfatti, Matilde Clarissa; Gerratana, Lorenzo; Tell, Gianluca; Puglisi, Fabio
Revisiting Two Decades of Research Focused on Targeting APE1 for Cancer Therapy: The Pros and Cons 1-gen-2023 Malfatti, M. C.; Bellina, A.; Antoniali, G.; Tell, G.
Role of condensates in modulating DNA repair pathways and its implication for chemoresistance 1-gen-2023 Dall'Agnese, G.; Dall'Agnese, A.; Banani, S. F.; Codrich, M.; Malfatti, M. C.; Antoniali, G.; Tell, G.
The APE1/NPM1 axis in triple negative breast cancer: prognostic and therapeutic implications 1-gen-2017 Malfatti, M. C.; Gerratana, L.; Di Loreto, C.; Puglisi, F.; Tell, G.