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The importance of redox state in liver damage. 1-gen-2004 Cesaratto, L; Vascotto, Carlo; Calligaris, S; Tell, Gianluca
Overoxidation of peroxiredoxins as an immediate and sensitive marker of oxidative stress in HepG2 cells and its application to the redox effects induced by ischemia/reperfusion in human liver 1-gen-2005 Cesaratto, Laura; Vascotto, Carlo; D'Ambrosio, Cr; Scaloni, A; Baccarani, Umberto; Paron, I; Damante, Giuseppe; Calligaris, S; Quadrifoglio, F; Tiribelli, C; Tell, Gianluca
Activation of human T lymphocytes under conditions similar to those that occur during exposure to microgravity: a proteomics study. 1-gen-2005 Risso, A.; Tell, G; Vascotto, C.; Costessi, A.; Simona, A.; Scaloni, A.; Cosulich, M. E.
Differential proteomic analysis of nuclear extracts from thyroid cell lines 1-gen-2006 Salzano, Am; Paron, I; Pines, A; Bachi, A; Talamo, F; Bivi, N; Vascotto, Carlo; Damante, Giuseppe; Quadrifoglio, F; Scaloni, A; Tell, Gianluca
Proteomic analysis of liver tissues subjected to early ischemia/reperfusion injury during human orthotopic liver transplantation RID D-8000-2011 1-gen-2006 Vascotto, Carlo; Cesaratto, Laura; D'Ambrosio, C; Scaloni, A; Avellini, C; Paron, I; Baccarani, Umberto; Adani, Gl; Tribelli, C; Quadrifoglio, F; Tell, Gianluca
Nucleotide receptors stimulation by extracellular ATP controls Hsp90 expression through APE1/Ref-1 in thyroid cancer cells: a novel tumorigenic pathway 1-gen-2006 Pines, Alex; Bivi, Nicoletta; Vascotto, Carlo; Romanello, M; D'Ambrosio, C; Scaloni, A; Damante, Giuseppe; Morisi, R; Filetti, S; Ferretti, E; Quadrifoglio, Franco; Tell, Gianluca
RbAp48 is a target of nuclear factor-kappa B activity in thyroid cancer 1-gen-2007 Pacifico, F; Paolillo, M; Chiappetta, G; Crescenzi, E; Arena, S; Scaloni, A; Monaco, M; Vascotto, Carlo; Tell, Gianluca; Formisano, S; Leonardi, A.
Oxidized Transthyretin in amniotic fluid as an early marker of preeclampsia 1-gen-2007 D' AMBROSIO, C.; DI LORETO, Carla; Fruscalzo, A.; Marchesoni, Diego; Quadrifoglio, F; Salzano, A. M.; Scaloni, A.; Tell, Gianluca; Vascotto, Carlo
Comparative Proteomic and Microarrays analysis to identify molecular changes associated to APE1/Ref-1 loss of expression. 1-gen-2007 Vascotto, Carlo; Cesaratto, L; Deganuto, M; Fantim, D; Quadrifoglio, F; Tell, Gianluca
Bilirubin-induced cell toxicity involves PTEN activation through APE 1/Ref-1-dependent pathway 1-gen-2007 Cesaratto, L; Calligaris, S; Vascotto, Carlo; Deganuto, M; Bellarosa, C; Quadrifoglio, F; Ostrow, Dj; Tiribelli, C; Tell, Gianluca
Redox proteomics and immunohistology to study molecular events during ischemia-reperfusion in human liver 1-gen-2007 Avellini, C; Baccarani, Umberto; Trevisan, G; Cesaratto, L; Vascotto, Carlo; D'Aurizio, F; Pandolfi, M; Adani, Gl; Tell, Gianluca
Structural basis of human Pax8 redox regulation from the unbound paired box domain 1-gen-2008 Codutti, L; VAN INGEN, H; Vascotto, Carlo; Fogolari, Federico; Corazza, A; Tell, Gianluca; Quadrifoglio, F; Viglino, P; Boelens, R; Esposito, Gennaro
Molecular and functional changes associated with APE1/Ref-1 loss of expression reveal its multifunctional nature in mammalian cells 1-gen-2008 Vascotto, Carlo; Cesaratto, Laura; Zeef, Lah; Deganuto, M; D'Ambrosio, C; Scaloni, A; Romanello, M; Delneri, D; Mitra, S; Kelley, Mr; Quadrifoglio, F; Tell, Gianluca
APE1/Ref-1 regulates PTEN expression mediated by EGR-1 1-gen-2008 Fantini, D; Vascotto, C.; Deganuto, M; Bivi, N; Gustincich, S; Marcon, G.; Quadrifoglio, F; Damante, G.; Bhakat, K. K; Mitra, S; Tell, G.
The solution structure of DNA-free Pax-8 paired box domain accounts for redox regulation of transcriptional activity in the pax protein family 1-gen-2008 Codutti, L.; VAN INGEN, H.; Vascotto, Carlo; Fogolari, Federico; Corazza, Alessandra; Tell, Gianluca; Quadrifoglio, F.; Viglino, P.; Boelens, R.; Esposito, Gennaro
The Neutrophil Gelatinase-Associated Lipocalin (NGAL), a NF-kB-regulated gene, is a survival factor for thyroid neoplastic cells. 1-gen-2008 Acquaviva, R.; Chiappetta, G.; Crescenzi, E.; Formisano, S.; Iannetti, A.; Lavorgna, A.; Leonardi, A.; Pacifico, F.; Salzano, A. M.; Scaloni, A.; Tell, Gianluca; Vascotto, Carlo; Vuttariello, E.
APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process 1-gen-2009 Vascotto, Carlo; Fantini, D; Romanello, M; Cesaratt, o L; Deganuto, M; Leonardi, A; Radicella, Jp; Kelley, Mr; D'Ambrosio, C; Scaloni, A; Quadrifoglio, F; Tell, Gianluca
Genome-wide analysis and proteomic studies reveal APE1/Ref-1 multifunctional role in mammalian cells. 1-gen-2009 Vascotto, Carlo; Cesaratto, Laura; Zeef, La; Deganuto, Marta; D'Ambrosio, C; Scaloni, A; Romanello, Milena; Damante, Giuseppe; Taglialatela, G; Delneri, D; Kelley, Mr; Mitra, S; Quadrifoglio, Franco; Tell, Gianluca
New insights in the mitochondrial localization of APE1, the major apurinic/apyrimidinic endonuclease in mammals 1-gen-2010 Bisetto, E; Domenis, Rossana; Comelli, Marina; Vascotto, Carlo; Cesaratto, L; Romanello, M; Quadrifoglio, F; Mavelli, Irene; Tell, Gianluca
Critical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions. 1-gen-2010 Fantini, Damiano; Vascotto, Carlo; Marasco, D; D'Ambrosio, C; Romanello, Milena; Vitagliano, L; Pedone, C; Poletto, Mattia; Cesaratto, Laura; Quadrifoglio, Franco; Scaloni, A; Radicella, Jp; Tell, Gianluca
Knock-in reconstitution studies reveal an unexpected role of Cys-65 in regulating APE1/Ref-1 subcellular trafficking and function 1-gen-2011 Vascotto, Carlo; Bisetto, Elena; Li, M; Zeef, Lah; Dambrosio, C; Domenis, Rossana; Comelli, Marina; Delneri, D; Scaloni, A; Altieri, F; Mavelli, Irene; Quadrifoglio, Franco; Kelley, Mr; Tell, Gianluca
Blockade of Base Excision Repair: Inhibition of Small Lesions Results in Big Consequences to Cancer Cells 1-gen-2011 Vascotto, Carlo; Fishel, M. L.
A New Mitochondrial Redox Regulator: Human AP endonuclease/Redox Factor APE1/Ref-1 modulates mitochondrial function after Oxidative Stress by Regulating Transcriptional Activity of NRF1 1-gen-2011 Li, Mx; Vascotto, Carlo; Xu, Sc; Dai, N; Qing, Y; Zhong, Zy; Tell, Gianluca; Wang, D.
Human AP endonuclease/redox factor APE1/ref-1modulates mitochondrial function after oxidative stress by regulating the transcriptional activity of NRF1. 1-gen-2012 Li, M; Vascotto, Carlo; Xu, S; Dai, N; Qing, Y; Zhong, Z; Tell, Gianluca; Wang, D.
Nucleolar accumulation of APE1 depends on charged Lysine residues that undergo acetylation upon genotoxic stress and modulate its BER activity in cells 1-gen-2012 Lirussi, L; Antoniali, G; Vascotto, Carlo; D’Ambrosio, C; Poletto, M; Romanello, M; Marasco, D; Leone, M; Quadrifoglio, F; Bhakat, Kk; Scaloni, A; Tell, Gianluca
DNA Base Excision Repair Therapeutics:Summary of Targets with a focus on APE1 1-gen-2013 Fishel, M; Vascotto, Carlo; Kelley, Mr
Combining RNAi and in vivo confocal microscopy analysis of the photoconvertible fluorescent protein Dendra2 to study a DNA repair protein 1-gen-2013 Tell, Gianluca; Di Piazza, M; Kamocka, Mm; Vascotto, Carlo
Specific Inhibition of the Redox Activity of Ape1/Ref-1 by E3330 Blocks Tnf-A-Induced Activation of Il-8 Production in Liver Cancer Cell Lines 1-gen-2013 Cesaratto, L; Codarin, E; Vascotto, Carlo; Leonardi, A; Kelley, Mr; Tiribelli, C; Tell, Gianluca
Alterations in the redox state and liver damage: Hints from the EASL Basic School of Hepatology 1-gen-2013 Tell, Gianluca; Vascotto, Carlo; Tiribelli, C.
Role of mutual interactions in the chemical and thermal stability of nucleophosmin NPM1 domains 1-gen-2013 Marasco, D; Ruggiero, A; Vascotto, Carlo; Poletto, M; Scognamiglio, Pl; Tell, Gianluca; Vitagliano, L.
Role of the unstructured N-terminal domain of the human Apurinic/Apyrimidinic Endonuclease 1 (hAPE1) in the modulation of its interaction with nucleic acids and Nucleophosmin (NPM1) 1-gen-2013 Poletto, M; Vascotto, Carlo; Scognamiglio, Pl; Lirussi, L; Marasco, D; Tell, Gianluca
Functional regulation of the apurinic/apyrimidinic endonuclease 1 by nucleophosmin: impact on tumor biology 1-gen-2014 Vascotto, Carlo; Lirussi, Lisa; Poletto, Mattia; Tiribelli, Mario; Damiani, Daniela; Fabbro, Dora; Damante, Giuseppe; Demple, B; Colombo, E; Tell, Gianluca
SIRT1 gene expression upon genotoxic damage is regulated by APE1 through nCaRE-promoter elements 1-gen-2014 Antoniali, G.; Lirussi, L.; D'Ambrosio, C.; Dal Piaz, F.; Vascotto, Carlo; Casarano, Elena; Marasco, D.; Scaloni, A.; Fogolari, Federico; Tell, Gianluca
Osteoblastic cell secretome: A novel role for progranulin during risedronate treatment 1-gen-2014 Romanello, M; Piatkowska, E; Antoniali, G; Cesaratto, Laura; Vascotto, Carlo; Iozzo, Rv; Delneri, D; Brancia, Fl
Expression and Prognostic Significance of APE1/Ref-1 and NPM1 Proteins in High-Grade Ovarian Serous Cancer 1-gen-2014 A. P., Londero; M., Orsaria; Tell, Gianluca; S., Marzinotto; V., Capodicasa; Poletto, Mattia; Vascotto, Carlo; C., Sacco; Mariuzzi, Laura
The redox function of APE1 is involved in the differentiation process of stem cells toward a neuronal cell fate 1-gen-2014 Domenis, Rossana; Bergamin, N; Gianfranceschi, G; Vascotto, Carlo; Romanello, M; Rigo, S; Vagnarelli, G; Faggiani, M; Parodi, Pier Camillo; Kelley, Mr; Beltrami, Carlo Alberto; Cesselli, Daniela; Tell, Gianluca; Beltrami, Antonio Paolo
Ex vivo molecular rejuvenation improves the therapeutic activity of senescent human cardiac stem cells in a mouse model of myocardial infarction. 1-gen-2014 E., Avolio; G., Gianfranceschi; Cesselli, Daniela; A., Caragnano; E., Athanasakis; R., Katare; M., Meloni; A., Palma; Barchiesi, Arianna; Vascotto, Carlo; B., Toffoletto; E., Mazzega; Finato, Nicoletta; G., Aresu; Livi, Ugolino; C., Emanueli; G., Scoles; C. A., Beltrami; P., Madeddu; Beltrami, Antonio Paolo
Oxidative Stress, Antioxidant Defenses, and the Liver 1-gen-2015 Vascotto, Carlo; Tiribelli, C.
Inhibitors of the apurinic/apyrimidinic endonuclease 1 (APE1)/nucleophosmin (NPM1) interaction that display anti-tumor properties 1-gen-2015 Poletto, Mattia; Malfatti, MATILDE CLARISSA; Dorjsuren, Dorjbal; Scognamiglio, Pasqualina L; Marasco, Daniela; Vascotto, Carlo; Jadhav, Ajit; Maloney, David J; Wilson, David M; Simeonov, Anton; Tell, Gianluca
Erratum: Functional regulation of the Apurinic/apyrimidinic endonuclease APE1 by Nucleophosmin (NPM1): Impact on tumor biology 1-gen-2015 Vascotto, Carlo; Lirussi, Lisa; Poletto, Mattia; Tiribelli, Mario; Damiani, Daniela; Fabbro, D.; Damante, Giuseppe; Demple, B.; Colombo, E.; Tell, Gianluca
Transcriptional up-regulation of APE1/Ref-1 in hepatic tumor: Role in hepatocytes resistance to oxidative stress and apoptosis 1-gen-2015 Di Maso, Vittorio; Mediavilla, María Gabriela; Vascotto, Carlo; Lupo, Francesco; Baccarani, Umberto; Avellini, Claudio; Tell, Gianluca; Tiribelli, Claudio; Crocè, Lory Saveria
Mitochondrial translocation of APE1 relies on the MIA pathway 1-gen-2015 Barchiesi, Arianna; Wasilewski, M; Chacinska, A; Tell, Gianluca; Vascotto, Carlo
Impairment of enzymatic antioxidant defenses is associated with bilirubin-induced neuronal cell death in the cerebellum of Ugt1 KO mice 1-gen-2015 Bortolussi, G; Codarin, Erika; Antoniali, Giulia; Vascotto, Carlo; Vodret, S; Arena, S; Cesaratto, Laura; Scaloni, A; Tell, Gianluca; Muro, Af
Understanding the basics for translating the base excision repair pathway from benchtop to bedside in cancer treatment 1-gen-2016 Vascotto, Carlo; Poletto, M.; Tell, Gianluca
Identification of tumorigenesis-related mRNAs associated with RNA-binding protein HuR in thyroid cancer cells 1-gen-2016 Baldan, Federica; Mio, Catia; Allegri, Lorenzo; Conzatti, Ketty; Toffoletto, Barbara; Puppin, Cinzia; Radovic, Slobodanka; Vascotto, Carlo; Russo, Diego; DI LORETO, Carla; Damante, Giuseppe
Isolation of mitochondria is necessary for precise quantification of mitochondrial DNA damage in human carcinoma samples. 1-gen-2017 Barchiesi, Arianna; Baccarani, Umberto; Billack, B; Tell, Gianluca; Vascotto, Carlo
Autophagy and Inflammasome Activation in Dilated Cardiomyopathy 1-gen-2019 Caragnano, Angela; Aleksova, Aneta; Bulfoni, Michela; Cervellin, Celeste; Rolle, Irene Giulia; Veneziano, Claudia; Barchiesi, Arianna; Mimmi, Maria Chiara; Vascotto, Carlo; Finato, Nicoletta; Sponga, Sandro; Livi, Ugolino; Isola, Miriam; Di Loreto, Carla; Bussani, Rossana; Sinagra, Gianfranco; Cesselli, Daniela; Beltrami, Antonio Paolo
Transcription, Processing, and Decay of Mitochondrial RNA in Health and Disease 1-gen-2019 Barchiesi, Arianna; Vascotto, Carlo
Mitochondrial Oxidative Stress Induces Rapid Intermembrane Space/Matrix Translocation of Apurinic/Apyrimidinic Endonuclease 1 Protein through TIM23 Complex 1-gen-2020 Barchiesi, A.; Bazzani, V.; Tolotto, V.; Elancheliyan, P.; Wasilewski, M.; Chacinska, A.; Vascotto, C.
Mitochondrial apurinic/apyrimidinic endonuclease 1 enhances mtDNA repair contributing to cell proliferation and mitochondrial integrity in early stages of hepatocellular carcinoma 1-gen-2020 Bazzani, V.; Barchiesi, A.; Radecka, D.; Pravisani, R.; Guadagno, A.; Di Loreto, C.; Baccarani, U.; Vascotto, C.
Mostrati risultati da 1 a 50 di 56
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