Cellular senescence processes affecting tissue resident stem cells are considered, at present, an hallmark of both aging and age-related pathologies. Therefore it is mandatory to address this problem with adequate techniques that could highlight the molecular alterations associated with this complex cellular response to stressors. Here we describe methods to characterize cardiac stem cell (CSC) senescence from a molecular and functional standpoint.
Cardiac stem cell senescence.
CESSELLI, Daniela;D'AURIZIO, Federica;MARCON, Patrizia;BERGAMIN, Natascha;BELTRAMI, Carlo Alberto;BELTRAMI, Antonio Paolo
2013-01-01
Abstract
Cellular senescence processes affecting tissue resident stem cells are considered, at present, an hallmark of both aging and age-related pathologies. Therefore it is mandatory to address this problem with adequate techniques that could highlight the molecular alterations associated with this complex cellular response to stressors. Here we describe methods to characterize cardiac stem cell (CSC) senescence from a molecular and functional standpoint.File in questo prodotto:
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