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Theoretical and Experimental Investigation of Methods for Enhancing the Energy Efficiency of CO2 Reverse Cycles

The increasing need for sustainable refrigeration and heat pump tech nologies has driven significant research interest towards the use of carbon dioxide (CO2) as a refrigerant. Despite its environmental advantages, the transcritical behaviour of CO2 systems often leads to reduced efficiency, especially under warm climatic conditions. This doctoral research investi gates multiple strategies to enhance the energy performance, operational f lexibility, and economic viability of CO2-based systems...

Essays on geopolitical risk in the financial system

This research work is composed of a trilogy of three researches that study the interconnectedness between geopolitical risk (GPR), which has been among the undisputed protagonists of the most recent years, and the financial system, with a particular focus on energy markets, bank lending and ESG performance of banks. The first research consists of a bibliometric literature review that is aimed at outlining and defining the intellectual and research architecture entailed in the topic of geopol...

Exploring entrepreneurship integrating human capital, business characteristics, and strategic decisions: The case of the wine sector in Veneto

This thesis stems from the collaboration between the Department of Management of the University of Verona and the Federazione Veneta delle Banche di Credito Cooperativo. This collaboration responds to shared knowledge gaps regarding the availability of specific and reliable entrepreneurial, financial and social information that can represent the characteristics of the production systems where banks operate. It aims to understand the dynamics of territorial systems and their potential future t...

Innovative technologies for the production and tracking of Extracellular Vesicles

Extracellular vesicles (EVs) have rapidly moved from being considered simple cellular by-products to becoming key mediators of intercellular communication with significant therapeutic and diagnostic potential. As their clinical potential expands, two parallel needs have become increasingly evident: the ability to produce EVs in a standardized, scalable and regulatory-compliant manner, and the availability of reliable tools to study how EVs are generated and released by cells. This work explor...

Interfering with the tumour microenvironment of glioblastoma: an in vitro study

Glioblastoma (GBM) is the most aggressive primary malignant tumour of the central nervous system (CNS), characterized by high invasiveness, resistance to therapy and frequent recurrence. Despite the current standard treatment, including surgical resection followed by radiotherapy and chemoradiotherapy, GBM patients face poor prognosis due to therapeutic resistance and tumour recurrence. A major contributor to GBM aggressiveness is the tumour microenvironment (TME), which promotes malignancy t...

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