Antiinflammatory drugs have greatly improved the quality of life and management of several rheumatic conditions. However, the benefits of antiinflammatory therapies should be weighed against the potential consequences, with careful evaluation of side effects. The aim of the present chapter is to summarize current evidence on potential cardiovascular effects of antiinflammatory therapies including either adverse or potentially desirable effects. Nonsteroidal antiinflammatory drugs (NSAIDs) and disease-modifying antirheumatic drugs (DMARDs) are reviewed, with a focus on hydroxychloroquine, methotrexate, sulfasalazine, minocycline, varespladib, leflunomide, and colchicine.
Desirable and Adverse Effects of Antiinflammatory Agents on the Heart
Imazio M.;
2017-01-01
Abstract
Antiinflammatory drugs have greatly improved the quality of life and management of several rheumatic conditions. However, the benefits of antiinflammatory therapies should be weighed against the potential consequences, with careful evaluation of side effects. The aim of the present chapter is to summarize current evidence on potential cardiovascular effects of antiinflammatory therapies including either adverse or potentially desirable effects. Nonsteroidal antiinflammatory drugs (NSAIDs) and disease-modifying antirheumatic drugs (DMARDs) are reviewed, with a focus on hydroxychloroquine, methotrexate, sulfasalazine, minocycline, varespladib, leflunomide, and colchicine.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
