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Class IIa HDACs repressive activities on MEF2-depedent transcription are associated with poor prognosis of ER+ breast tumors. 1-gen-2013 Clocchiatti, A; Di Giorgio, E; Ingrao, S; Meyer Almes, Fj; Tripodo, C; Brancolini, Claudio
Beside the MEF2 axis: Unconventional functions of HDAC4. 1-gen-2013 Clocchiatti, A; DI Giorgio, E; Demarchi, F; Brancolini, Claudio
MEF2 is a converging hub for HDAC4 and PI3K/Akt-induced transformation. 1-gen-2013 Di Giorgio, E; Clocchiatti, A; Piccinin, S; Sgorbissa, A; Viviani, G; Peruzzo, P; Romeo, S; Rossi, S; Dei Tos, Ap; Maestro, R; Brancolini, Claudio
METABOLIC ALTERATION AND MITOCHONDRIAL BIOENERGETIC PROFILE IN HDAC4-DRIVEN TUMORIGENESIS 1-gen-2013 Peruzzo, Paolo; DI GIORGIO, Eros; Mavelli, Irene; Brancolini, Claudio
The MEF2-HDAC axis controls proliferation of mammary epithelial cells and acini formation in vitro 1-gen-2015 Clocchiatti, A.; Di Giorgio, E.; Viviani, G.; Streuli, C.; Sgorbissa, A.; Picco, R.; Cutano, V.; Brancolini, Claudio
Selective class IIa HDAC inhibitors: myth or reality. 1-gen-2015 Di Giorgio, E; Gagliostro, E; Brancolini, Claudio
The control operated by the cell cycle machinery on mef2 stability contributes to the downregulation of cdkn1a and entry into s phase 1-gen-2015 DI GIORGIO, Eros; Gagliostro, Enrico; Clocchiatti, Andrea; Brancolini, Claudio
THE REPRESSION OF MEF2 TRANSCRIPTION FACTORS EXERTED BY CLASS IIA HDACS AND THEIR DEGRADATION STIMULATED BY CDK4 DETERMINE THE ACQUISITION OF HALLMARKS OF TRANSFORMATION IN FIBROBLASTS. 10-apr-2015 Di Giorgio, Eros
Potent and Selective Non-hydroxamate Histone Deacetylase 8 Inhibitors 1-gen-2016 Kleinschek, Alexander; Meyners, Christian; Digiorgio, Eros; Brancolini, Claudio; Meyer almes, Franz josef
Transformation by different oncogenes relies on specific metabolic adaptations 1-gen-2016 Peruzzo, Paolo; Comelli, Marina; Di Giorgio, Eros; Franforte, Elisa; Mavelli, Irene; Brancolini, Claudio
Regulation of class IIa HDAC activities: It is not only matter of subcellular localization 1-gen-2016 DI GIORGIO, Eros; Brancolini, Claudio
The co-existence of transcriptional activator and transcriptional repressor MEF2 complexes influences tumor aggressiveness 1-gen-2017 Di Giorgio, Eros; Franforte, Elisa; Cefalù, Sebastiano; Rossi, Sabrina; Dei Tos, Angelo Paolo; Brenca, Monica; Polano, Maurizio; Maestro, Roberta; Paluvai, Harikrishnareddy; Picco, Raffaella; Brancolini, Claudio
Unscheduled HDAC4 repressive activity in human fibroblasts triggers TP53-dependent senescence and favors cell transformation 1-gen-2018 Paluvai, Harikrishnareddy; Di Giorgio, Eros; Brancolini, Claudio
MEF2 and the tumorigenic process, hic sunt leones 1-gen-2018 Di Giorgio, Eros; Hancock, Wayne W.; Brancolini, Claudio
Genetic programs driving oncogenic transformation: Lessons from in vitro models 1-gen-2019 Di Giorgio, E.; Paluvai, H.; Picco, R.; Brancolini, C.
HDAC7-mediated control of tumour microenvironment maintains proliferative and stemness competence of human mammary epithelial cells 1-gen-2019 Cutano, V.; Di Giorgio, E.; Minisini, Martina; Picco, R.; Dalla, E.; Brancolini, C.
Different class IIa HDACs repressive complexes regulate specific epigenetic responses related to cell survival in leiomyosarcoma cells 1-gen-2020 Di Giorgio, E.; Dalla, E.; Franforte, E.; Paluvai, H.; Minisini, M.; Trevisanut, M.; Picco, R.; Brancolini, C.
The Histone Code of Senescence 1-gen-2020 Paluvai, Harikrishnareddy; Di Giorgio, Eros; Brancolini, Claudio
Inhibiting the coregulator CoREST impairs Foxp3+ Treg function and promotes antitumor immunity 1-gen-2020 Xiong, Y.; Wang, L.; Giorgio, E. D.; Akimova, T.; Beier, U. H.; Han, R.; Trevisanut, M.; Kalin, J. H.; Cole, P. A.; Hancock, W. W.
GSK3β is a key regulator of the ROS-dependent necrotic death induced by the quinone DMNQ 1-gen-2020 Ciotti, S.; Iuliano, L.; Cefalu, S.; Comelli, M.; Mavelli, I.; Di Giorgio, E.; Brancolini, C.
A Biological Circuit Involving Mef2c, Mef2d, and Hdac9 Controls the Immunosuppressive Functions of CD4+Foxp3+ T-Regulatory Cells 1-gen-2021 Di Giorgio, E.; Wang, L.; Xiong, Y.; Christensen, L. M.; Akimova, T.; Han, R.; Samanta, A.; Trevisanut, M.; Brancolini, C.; Beier, U. H.; Hancock, W. W.
Enhancing proteotoxic stress in leiomyosarcoma cells triggers mitochondrial dysfunctions, cell death, and antitumor activity in vivo 1-gen-2021 Iuliano, L.; Drioli, S.; Pignochino, Y.; Cafiero, C. M.; Minisini, M.; D'Este, F.; Picco, R.; Dalla, E.; Giordano, G.; Grignani, G.; Di Giorgio, E.; Benedetti, F.; Felluga, F.; Brancolini, C.
HDAC4 degradation during senescence unleashes an epigenetic program driven by AP-1/p300 at selected enhancers and super-enhancers 1-gen-2021 Di Giorgio, E.; Paluvai, H.; Dalla, E.; Ranzino, L.; Renzini, A.; Moresi, V.; Minisini, M.; Picco, R.; Brancolini, C.
A regulative epigenetic circuit supervised by HDAC7 represses IGFBP6 and IGFBP7 expression to sustain mammary stemness 1-gen-2021 Di Giorgio, E.; Cutano, V.; Minisini, M.; Tolotto, V.; Dalla, E.; Brancolini, C.
Quis custodiet ipsos custodes (Who controls the controllers)? two decades of studies on HDAC9 1-gen-2021 Brancolini, C.; Di Giorgio, E.; Formisano, L.; Gagliano, T.
Endogenous Retroviruses (ERVs): Does RLR (RIG-I-Like Receptors)-MAVS Pathway Directly Control Senescence and Aging as a Consequence of ERV De-Repression? 1-gen-2022 DI GIORGIO, Eros
Cytoplasmic HDAC4 regulates the membrane repair mechanism in Duchenne muscular dystrophy 1-gen-2022 Renzini, A.; Marroncelli, N.; Cavioli, G.; Di Francescantonio, S.; Forcina, L.; Lambridis, A.; Di Giorgio, E.; Valente, S.; Mai, A.; Brancolini, C.; Giampietri, C.; Magenta, A.; De Santa, F.; Adamo, S.; Coletti, D.; Moresi, V.
Photosensitization of pancreatic cancer cells by cationic alkyl-porphyrins in free form or engrafted into POPC liposomes: The relationship between delivery mode and mechanism of cell death 1-gen-2022 DI GIORGIO, Eros; Ferino, Annalisa; Choudhary, Himanshi; Löffler, Phillip M. G.; D'Este, Francesca; Rapozzi, Valentina; Tikhomirov, Alexander; Shchekotikhin, Andrey; Vogel, Stefan; Xodo, Luigi E.
Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription 1-gen-2022 Minisini, Martina; Di Giorgio, Eros; Kerschbamer, Emanuela; Dalla, Emiliano; Faggiani, Massimo; Franforte, Elisa; Meyer-Almes, Franz-Josef; Ragno, Rino; Antonini, Lorenzo; Mai, Antonello; Fiorentino, Francesco; Rotili, Dante; Chinellato, Monica; Perin, Stefano; Cendron, Laura; Weichenberger, Christian X; Angelini, Alessandro; Brancolini, Claudio
Super-enhancer landscape rewiring in cancer: The epigenetic control at distal sites 1-gen-2023 Di Giorgio, E.; Benetti, R.; Kerschbamer, E.; Xodo, L.; Brancolini, C.
Dual-targeting peptides@PMO, a mimetic to the pro-apoptotic protein Smac/DIABLO for selective activation of apoptosis in cancer cells 1-gen-2023 Di Giorgio, E.; Ferino, A.; Huang, W.; Simonetti, S.; Xodo, L.; De Marco, R.
Fetal growth at term and placental oxidative stress in a tissue micro-array model: a histological and immunohistochemistry study 1-gen-2023 Xodo, S.; Celante, L.; Liviero, S.; Orsaria, M.; Mariuzzi, L.; De Luca, M.; Damante, G.; Driul, L.; Cagnacci, A.; Ferino, A.; Di Giorgio, E.; Xodo, L.; Londero, A. P.
Suppression of the KRAS-NRF2 axis shifts arginine into the phosphocreatine energy system in pancreatic cancer cells 1-gen-2023 Di Giorgio, Eros; Choudhary, Himanshi; Ferino, Annalisa; Cortolezzis, Ylenia; Dalla, Emiliano; D'Este, Francesca; Comelli, Marina; Rapozzi, Valentina; Xodo, Luigi E
Folding of Class IIa HDAC Derived Peptides into α-helices Upon Binding to Myocyte Enhancer Factor-2 in Complex with DNA 1-gen-2024 Chinellato, M.; Perin, S.; Carli, A.; Lastella, L.; Biondi, B.; Borsato, G.; Di Giorgio, E.; Brancolini, C.; Cendron, L.; Angelini, A.
NRF2 interacts with distal enhancer and inhibits nitric oxide synthase 2 expression in KRAS-driven pancreatic cancer cells 1-gen-2024 Di Giorgio, Eros; Cortolezzis, Ylenia; Gualandi, Nicolò; Agostini, Francesca; Rapozzi, Valentina; Xodo, Luigi E
HDAC4 influences the DNA damage response and counteracts senescence by assembling with HDAC1/HDAC2 to control H2BK120 acetylation and homology-directed repair 1-gen-2024 Di Giorgio, E.; Dalla, E.; Tolotto, V.; D'Este, F.; Paluvai, H.; Ranzino, L.; Brancolini, C.
T-regulatory cells require Sin3a for stable expression of Foxp3 1-gen-2024 Christensen, L. M.; Akimova, T.; Wang, L.; Han, R.; Samanta, A.; Di Giorgio, E.; Hancock, W. W.
Changes in chromatin accessibility and transcriptional landscape induced by HDAC inhibitors in TP53 mutated patient-derived colon cancer organoids 1-gen-2024 Gagliano, Teresa; Kerschbamer, Emanuela; Baccarani, Umberto; Minisini, Martina; Di Giorgio, Eros; Dalla, Emiliano; Weichenberger, Christian X; Cherichi, Vittorio; Terrosu, Giovanni; Brancolini, Claudio
Transcription of endogenous retroviruses in senescent cells contributes to the accumulation of double-stranded RNAs that trigger an anti-viral response that reinforces senescence 1-gen-2024 Di Giorgio, Eros; Ranzino, Liliana; Tolotto, Vanessa; Dalla, Emiliano; Burelli, Matteo; Gualandi, Nicolò; Brancolini, Claudio
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