Bacterial pneumonia in newborns often leads to surfactant deficiency or dysfunction, as surfactant is inactivated or its production/turnover impaired. No data are available in vivo in humans on the mechanism of surfactant depletion in neonatal pneumonia. We studied the kinetics of surfactant's major component, disaturated-phosphatidylcholine (DSPC), in neonatal pneumonia, and we compared our findings with those obtained from control newborn lungs.
Titolo: | In vivo effect of pneumonia on surfactant disaturated-phosphatidylcholine kinetics in newborn infants |
Autori: | |
Data di pubblicazione: | 2014 |
Rivista: | |
Abstract: | Bacterial pneumonia in newborns often leads to surfactant deficiency or dysfunction, as surfactant is inactivated or its production/turnover impaired. No data are available in vivo in humans on the mechanism of surfactant depletion in neonatal pneumonia. We studied the kinetics of surfactant's major component, disaturated-phosphatidylcholine (DSPC), in neonatal pneumonia, and we compared our findings with those obtained from control newborn lungs. |
Handle: | http://hdl.handle.net/11390/1071359 |
Appare nelle tipologie: | 1.1 Articolo in rivista |
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