We have followed, at 3, 6, 12, 24 months after the onset of therapy, 584 patients with refractory Generalized and Partial Epilepsy, started on LTG as add-on. Drop-out accounted for 32% of the SGE patients, 23% of the CGE, 13% IGE, and 40% EP. Lack of efficacy and side effect accounted for 71% and 29% respectively of drop-out rate. Most frequent adverse events were skin rashes and psychological disturbances.
Studio triveneto sulla lamotrigina: Motivi di sospensione della terapia
DE MARCO, PASQUALE;BERGONZI, Paolo;COSTA, PIETRO;CRISTOFORI, Guido;GIGLI, Gian Luigi;LUCCI, Bruno;MARINIG, Roberto;PANICO, ANNA CLARA;PAULETTO, GIADA;PRIVATO, Fiorenza;SERENA, MARINA;TOLDO, MASSIMILIANO;
2002-01-01
Abstract
We have followed, at 3, 6, 12, 24 months after the onset of therapy, 584 patients with refractory Generalized and Partial Epilepsy, started on LTG as add-on. Drop-out accounted for 32% of the SGE patients, 23% of the CGE, 13% IGE, and 40% EP. Lack of efficacy and side effect accounted for 71% and 29% respectively of drop-out rate. Most frequent adverse events were skin rashes and psychological disturbances.File in questo prodotto:
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