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EnglishThe possibility to routinely sequence a genome has became a reality in the last years. In this thesis the most pressing problems of today bioinformatics are discussed. Moreover, new solutions are proposed in particular: a new short string aligner designed to align the myriads of sequences generated by state of the art sequencers against a reference genome, a new reference guided assembly pipeline, and a new assembly validation method
Next generation sequencing revolution challenges: search, assemble, and validate genomes / Francesco Vezzi - Udine : Università degli Studi di Udine. , 2012 Mar 15. ((24. ciclo
| Titolo: | Next generation sequencing revolution challenges: search, assemble, and validate genomes |
| Autori: | |
| Data di pubblicazione: | 15-mar-2012 |
| Citazione: | Next generation sequencing revolution challenges: search, assemble, and validate genomes / Francesco Vezzi - Udine : Università degli Studi di Udine. , 2012 Mar 15. ((24. ciclo |
| Abstract: | The possibility to routinely sequence a genome has became a reality in the last years. In this thesis the most pressing problems of today bioinformatics are discussed. Moreover, new solutions are proposed in particular: a new short string aligner designed to align the myriads of sequences generated by state of the art sequencers against a reference genome, a new reference guided assembly pipeline, and a new assembly validation method |
| Handle: | http://hdl.handle.net/11390/1132268 |
| Appare nelle tipologie: | 8.2 Tesi di Dottorato (OpenUniud) |
File in questo prodotto:
| File | Descrizione | Tipologia | Licenza | |
|---|---|---|---|---|
| 10990_121_FrancescoVezzi_PhD_thesis.pdf | Tesi di dottorato | Non specificato | Open Access Visualizza/Apri |
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