The possibility to routinely sequence a genome has became a reality in the last years. In this thesis the most pressing problems of today bioinformatics are discussed. Moreover, new solutions are proposed in particular: a new short string aligner designed to align the myriads of sequences generated by state of the art sequencers against a reference genome, a new reference guided assembly pipeline, and a new assembly validation method
Next generation sequencing revolution challenges: search, assemble, and validate genomes / Francesco Vezzi - Udine. , 2012 Mar 15. 24. ciclo
Next generation sequencing revolution challenges: search, assemble, and validate genomes
Vezzi, Francesco
2012-03-15
Abstract
The possibility to routinely sequence a genome has became a reality in the last years. In this thesis the most pressing problems of today bioinformatics are discussed. Moreover, new solutions are proposed in particular: a new short string aligner designed to align the myriads of sequences generated by state of the art sequencers against a reference genome, a new reference guided assembly pipeline, and a new assembly validation methodFile in questo prodotto:
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