Transposition of the great arteries (TGA) is a cyanotic congenital heart defect that requires surgical correction, with the use of cardiopulmonary-bypass (CPB), usually within 3 weeks of life. The use of CPB in open heart surgery results in brain hypoperfusion and in a powerful systemic inflammatory response and oxidative stress.
Urinary metabolomics reveals kynurenine pathway perturbation in newborns with transposition of great arteries after surgical repair
Simonato M.;Cogo P.
2019-01-01
Abstract
Transposition of the great arteries (TGA) is a cyanotic congenital heart defect that requires surgical correction, with the use of cardiopulmonary-bypass (CPB), usually within 3 weeks of life. The use of CPB in open heart surgery results in brain hypoperfusion and in a powerful systemic inflammatory response and oxidative stress.File in questo prodotto:
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Urinary Metabolomics Reveals Kynurenine - Metabolomics 2019.pdf
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