Most intraductal carcinoma of the prostate (IDC-P) lesions are likely derived from retrograde spreading of cancer cells into adjacent benign ducts. Tumor cells in IDC-P frequently display a high degree of genomic instability. Germline mutations in DNA repair genes are implicated in IDC-P tumorigenesis.
Intraductal Carcinoma of the Prostate: Pathogenesis and Molecular Perspectives
Cimadamore A.;
2020-01-01
Abstract
Most intraductal carcinoma of the prostate (IDC-P) lesions are likely derived from retrograde spreading of cancer cells into adjacent benign ducts. Tumor cells in IDC-P frequently display a high degree of genomic instability. Germline mutations in DNA repair genes are implicated in IDC-P tumorigenesis.File in questo prodotto:
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