Attenzione: i dati modificati non sono ancora stati salvati. Per confermare inserimenti o cancellazioni di voci è necessario confermare con il tasto SALVA/INSERISCI in fondo alla pagina
IRIS
Introduction: Infective endocarditis (IE) has undergone important changes in its epidemiology worldwide. Methods: The study aimed to compare IE epidemiological features and outcomes according to predefined European regions and between two different time periods in the twenty-first century. Results: IE cases from 13 European countries were included. Two periods were considered: 2000–2006 and 2008–2012. Two European regions were considered, according to the United Nations geoscheme for Europe: Southern (SE) and Northern–Central Europe (NCE). Comparisons were performed between regions and periods. A total of 4195 episodes of IE were included, 2113 from SE and 2082 from NCE; 2787 cases were included between 2000 and 2006 and 1408 between 2008 and 2012. Median (IQR) age was 63.7 (49–74) years and 69.4% were males. Native valve IE (NVE), prosthetic valve IE (PVE), and device-related IE were diagnosed in 68.3%, 23.9%, and 7.8% of cases, respectively; 52% underwent surgery and 19.3% died during hospitalization. NVE was more prevalent in NCE, whereas device-related IE was more frequent in SE. Higher age, acute presentation, hemodialysis, cancer, and diabetes mellitus all were more prevalent in the second period. NVE decreased and PVE and device-related IE both increased in the second period. Surgical treatment also increased from 48.7% to 58.4% (p < 0.01). In-hospital and 6-month mortality rates were comparable between regions and significantly decreased in the second period. Conclusions: Despite an increased complexity of IE cases, prognosis improved in recent years with a significant decrease in 6-month mortality. Outcome did not differ according to the European region (SE versus NCE). Graphical Abstract: [Figure not available: see fulltext.]
Epidemiological Changes and Improvement in Outcomes of Infective Endocarditis in Europe in the Twenty-First Century: An International Collaboration on Endocarditis (ICE) Prospective Cohort Study (2000–2012)
Ambrosioni J.;Hernandez-Meneses M.;Durante-Mangoni E.;Tattevin P.;Olaison L.;Freiberger T.;Hurley J.;Hannan M. M.;Chu V.;Hoen B.;Moreno A.;Cuervo G.;Llopis J.;Miro J. M.;Clara L.;Sanchez M.;Casabe J.;Cortes C.;Nacinovich F.;Oses P. F.;Ronderos R.;Sucari A.;Thierer J.;Altclas J.;Kogan S.;Spelman D.;Athan E.;Harris O.;Kennedy K.;Tan R.;Gordon D.;Papanicolas L.;Korman T.;Kotsanas D.;Dever R.;Jones P.;Konecny P.;Lawrence R.;Rees D.;Ryan S.;Feneley M. P.;Harkness J.;Jones P.;Ryan S.;Jones P.;Ryan S.;Jones P.;Post J.;Reinbott P.;Ryan S.;Gattringer R.;Wiesbauer F.;Andrade A. R.;de Brito A. C. P.;Guimaraes A. C.;Grinberg M.;Mansur A. J.;Siciliano R. F.;Strabelli T. M. V.;Vieira M. L. C.;de Medeiros Tranchesi R. A.;Paiva M. G.;Fortes C. Q.;de Oliveira Ramos A.;Weksler C.;Ferraiuoli G.;Golebiovski W.;Lamas C.;Karlowsky J. A.;Keynan Y.;Morris A. M.;Rubinstein E.;Jones S. B.;Garcia P.;Cereceda M.;Fica A.;Mella R. M.;Fernandez R.;Franco L.;Gonzalez J.;Jaramillo A. N.;Barsic B.;Bukovski S.;Krajinovic V.;Pangercic A.;Rudez I.;Vincelj J.;Freiberger T.;Pol J.;Zaloudikova B.;Ashour Z.;El Kholy A.;Mishaal M.;Osama D.;Rizk H.;Aissa N.;Alauzet C.;Alla F.;Campagnac C.;Doco-Lecompte T.;Selton-Suty C.;Casalta J. -P.;Fournier P. -E.;Habib G.;Raoult D.;Thuny F.;Delahaye F.;Delahaye A.;Vandenesch F.;Donal E.;Donnio P. Y.;Flecher E.;Michelet C.;Revest M.;Tattevin P.;Chevalier F.;Jeu A.;Remadi J. P.;Rusinaru D.;Tribouilloy C.;Bernard Y.;Chirouze C.;Hoen B.;Leroy J.;Plesiat P.;Naber C.;Neuerburg C.;Mazaheri B.;Naber C.;Neuerburg C.;Athanasia S.;Deliolanis I.;Giamarellou H.;Thomas T.;Giannitsioti E.;Mylona E.;Paniara O.;Papanicolaou K.;Pyros J.;Skoutelis A.;Mylona E.;Paniara O.;Papanikolaou K.;Pyros J.;Skoutelis A.;Sharma G.;Francis J.;Nair L.;Thomas V.;Venugopal K.;Hannan M. M.;Hurley J. P.;Wanounou M.;Gilon D.;Israel S.;Korem M.;Strahilevitz J.;Rubinstein E.;Strahilevitz J.;Iossa D.;Orlando S.;Ursi M. P.;Pafundi P. C.;D'Amico F.;Bernardo M.;Cuccurullo S.;Dialetto G.;Covino F. E.;Manduca S.;Corte A. D.;De Feo M.;Tripodi M. F.;Cecchi E.;De Rosa F.;Forno D.;Imazio M.;Trinchero R.;Grossi P.;Lattanzio M.;Toniolo A.;Goglio A.;Raglio A.;Ravasio V.;Rizzi M.;Suter F.;Carosi G.;Magri S.;Signorini L.;Kanafani Z.;Kanj S. S.;Sharif-Yakan A.;Abidin I.;Tamin S. S.;Martinez E. R.;Nieto G. I. S.;van der Meer J. T. M.;Chambers S.;Holland D.;Morris A.;Raymond N.;Read K.;Murdoch D. R.;Dragulescu S.;Ionac A.;Mornos C.;Butkevich O. M.;Chipigina N.;Kirill O.;Vadim K.;Vinogradova T.;Edathodu J.;Halim M.;Liew Y. -Y.;Tan R. -S.;Lejko-Zupanc T.;Logar M.;Mueller-Premru M.;Commerford P.;Commerford A.;Deetlefs E.;Hansa C.;Ntsekhe M.;Almela M.;Ambrosioni J.;Azqueta M.;Brunet M.;Castro P.;De Lazzari E.;Falces C.;Fuster D.;Fita G.;Garcia-de-la-Maria C.;Garcia-Gonzalez J.;Gatell J. M.;Llopis J.;Marco F.;Miro J. M.;Moreno A.;Ortiz J.;Ninot S.;Pare J. C.;Pericas J. M.;Quintana E.;Ramirez J.;Rovira I.;Sandoval E.;Sitges M.;Tellez A.;Tolosana J. M.;Vidal B.;Vila J.;Anguera I.;Font B.;Guma J. R.;Bermejo J.;Bouza E.;Fernandez M. A. G.;Marin V. G. -R. M.;Munoz P.;Pedromingo M.;Roda J.;Rodriguez-Creixems M.;Solis J.;Almirante B.;Fernandez-Hidalgo N.;Tornos P.;de Alarcon A.;Parra R.;Alestig E.;Johansson M.;Olaison L.;Snygg-Martin U.;Pachirat O.;Pachirat P.;Pussadhamma B.;Senthong V.;Casey A.;Elliott T.;Lambert P.;Watkin R.;Eyton C.;Klein J. L.;Bradley S.;Kauffman C.;Bedimo R.;Chu V. H.;Corey G. R.;Crowley A. L.;Douglas P.;Drew L.;Fowler V. G.;Holland T.;Lalani T.;Mudrick D.;Samad Z.;Sexton D.;Stryjewski M.;Wang A.;Woods C. W.;Lerakis S.;Cantey R.;Steed L.;Wray D.;Dickerman S. A.;Bonilla H.;DiPersio J.;Salstrom S. -J.;Baddley J.;Patel M.;Peterson G.;Stancoven A.;Levine D.;Riddle J.;Rybak M.;Cabell C. H.;Baloch K.;Chu V. H.;Corey G. R.;Dixon C. C.;Fowler V. G.;Harding T.;Jones-Richmond M.;Park L. P.;Sanderford B.;Stafford J.;Anstrom K.;Bayer A. S.;Cabell C. H.;Chu V. H.;Corey G. R.;Fowler V. G.;Hoen B.;Karchmer A. W.;Miro J. M.;Wang A.;Bayer A. S.;Cabell C. H.;Chu V.;Corey G. R.;Durack D. T.;Eykyn S.;Fowler V. G.;Hoen B.;Miro J. M.;Moreillon P.;Olaison L.
2023-01-01
Abstract
Introduction: Infective endocarditis (IE) has undergone important changes in its epidemiology worldwide. Methods: The study aimed to compare IE epidemiological features and outcomes according to predefined European regions and between two different time periods in the twenty-first century. Results: IE cases from 13 European countries were included. Two periods were considered: 2000–2006 and 2008–2012. Two European regions were considered, according to the United Nations geoscheme for Europe: Southern (SE) and Northern–Central Europe (NCE). Comparisons were performed between regions and periods. A total of 4195 episodes of IE were included, 2113 from SE and 2082 from NCE; 2787 cases were included between 2000 and 2006 and 1408 between 2008 and 2012. Median (IQR) age was 63.7 (49–74) years and 69.4% were males. Native valve IE (NVE), prosthetic valve IE (PVE), and device-related IE were diagnosed in 68.3%, 23.9%, and 7.8% of cases, respectively; 52% underwent surgery and 19.3% died during hospitalization. NVE was more prevalent in NCE, whereas device-related IE was more frequent in SE. Higher age, acute presentation, hemodialysis, cancer, and diabetes mellitus all were more prevalent in the second period. NVE decreased and PVE and device-related IE both increased in the second period. Surgical treatment also increased from 48.7% to 58.4% (p < 0.01). In-hospital and 6-month mortality rates were comparable between regions and significantly decreased in the second period. Conclusions: Despite an increased complexity of IE cases, prognosis improved in recent years with a significant decrease in 6-month mortality. Outcome did not differ according to the European region (SE versus NCE). Graphical Abstract: [Figure not available: see fulltext.]
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11390/1327217
Citazioni
ND
60
ND
social impact
Conferma cancellazione
Sei sicuro che questo prodotto debba essere cancellato?
simulazione ASN
Il report seguente simula gli indicatori relativi alla propria produzione scientifica in relazione alle soglie ASN 2023-2025 del proprio SC/SSD. Si ricorda che il superamento dei valori soglia (almeno 2 su 3) è requisito necessario ma non sufficiente al conseguimento dell'abilitazione. La simulazione si basa sui dati IRIS e sugli indicatori bibliometrici alla data indicata e non tiene conto di eventuali periodi di congedo obbligatorio, che in sede di domanda ASN danno diritto a incrementi percentuali dei valori. La simulazione può differire dall'esito di un’eventuale domanda ASN sia per errori di catalogazione e/o dati mancanti in IRIS, sia per la variabilità dei dati bibliometrici nel tempo. Si consideri che Anvur calcola i valori degli indicatori all'ultima data utile per la presentazione delle domande.
La presente simulazione è stata realizzata sulla base delle specifiche raccolte sul tavolo ER del Focus Group IRIS coordinato dall’Università di Modena e Reggio Emilia e delle regole riportate nel DM 589/2018 e allegata Tabella A. Cineca, l’Università di Modena e Reggio Emilia e il Focus Group IRIS non si assumono alcuna responsabilità in merito all’uso che il diretto interessato o terzi faranno della simulazione. Si specifica inoltre che la simulazione contiene calcoli effettuati con dati e algoritmi di pubblico dominio e deve quindi essere considerata come un mero ausilio al calcolo svolgibile manualmente o con strumenti equivalenti.
