Technetium-labeled methylene diphosphonate bone scan (BS) is the most commonly used imaging test to screen for skeletal metastases in patients with breast cancer. Since its introduction into clinical practice, a large number of studies have been conducted to explore the role of BS in the baseline staging work-up at the time of breast cancer diagnosis. Even though the policy of offering preoperative or perioperative BS is still widely diffuse, a lot of evidence in the literature suggests that routine BS examinations are not cost-effective and should be recommended in selected cases only. Based on current guidelines, the use of BS as a staging procedure is considered appropriate in patients with a high pre-test probability (prevalence) of bone metastases. This category is represented by patients with newly diagnosed high-risk breast cancer (i.e. pN2 or T4/pT4) or with symptoms or laboratory signs suspicious for bone involvement

Bone Scan for Baseline Staging in Invasive Breast Cancer at the Time of Primary Presentation

PUGLISI, Fabio;
2007-01-01

Abstract

Technetium-labeled methylene diphosphonate bone scan (BS) is the most commonly used imaging test to screen for skeletal metastases in patients with breast cancer. Since its introduction into clinical practice, a large number of studies have been conducted to explore the role of BS in the baseline staging work-up at the time of breast cancer diagnosis. Even though the policy of offering preoperative or perioperative BS is still widely diffuse, a lot of evidence in the literature suggests that routine BS examinations are not cost-effective and should be recommended in selected cases only. Based on current guidelines, the use of BS as a staging procedure is considered appropriate in patients with a high pre-test probability (prevalence) of bone metastases. This category is represented by patients with newly diagnosed high-risk breast cancer (i.e. pN2 or T4/pT4) or with symptoms or laboratory signs suspicious for bone involvement
File in questo prodotto:
File Dimensione Formato  
Puglisi et al__Breast Care 2007.pdf

non disponibili

Tipologia: Altro materiale allegato
Licenza: Non pubblico
Dimensione 407.62 kB
Formato Adobe PDF
407.62 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11390/696203
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 6
  • ???jsp.display-item.citation.isi??? 6
social impact