The Pd/CeO2 system behaves as an efficient precatalyst for the Suzuki–Miyaura cross-coupling under mild conditions (298 K, in air) in ethanol/water. A broad range of aryl bromides, including those deactivated, and arylboronic acids underwent Suzuki–Miyaura coupling with quantitative GC yields of asymmetric biaryls. Isolated yields and purity of the coupling products were good to excellent. A careful investigation through a series of suitable tests unequivocally showed that the C–C cross-coupling is accomplished via homogeneous mechanism by leached palladium(0). Noticeably, the Pd/CeO2 system can be recycled at least ten times without loss of activity.
"An Efficient and Reusable Catalyst Based on Pd/CeO2 for the Room Temperature Aerobic Suzuki-Miyaura Reaction in Water/Ethanol"
COLUSSI, Sara;DEL ZOTTO, Alessandro;TROVARELLI, Alessandro
2010-01-01
Abstract
The Pd/CeO2 system behaves as an efficient precatalyst for the Suzuki–Miyaura cross-coupling under mild conditions (298 K, in air) in ethanol/water. A broad range of aryl bromides, including those deactivated, and arylboronic acids underwent Suzuki–Miyaura coupling with quantitative GC yields of asymmetric biaryls. Isolated yields and purity of the coupling products were good to excellent. A careful investigation through a series of suitable tests unequivocally showed that the C–C cross-coupling is accomplished via homogeneous mechanism by leached palladium(0). Noticeably, the Pd/CeO2 system can be recycled at least ten times without loss of activity.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
