In this work, the results of the application of organic expanded porphyrins in the disinfection of water by the photodynamic inactivation (PDI) technique are presented. The photoinactivation properties of a novel, expanded porphyrin, namely 20-(4-carboxyphenyl)-2,13-dimethyl-3,12-diethyl-(22π) pentaphyrin (PCCox), were tested in the disinfection of water using Staphylococcus aureus as a Gram-positive bacteria model. The data showed that PCCox was effective against S. aureus bacteria at nanomolar concentrations. The variation with irradiation time and concentration was studied using both a multi-LED monochromatic light (λ ¼ 470 nm) and an incandescent light bulb with a wide emission spectrum. A PCCox dosage of 5 μM was sufficient to achieve a 99.997% abatement of S. aureus within 1 h of 40 W/m2 irradiation with monochromatic light (λ ¼ 470 nm), whereas under the same conditions using irradiation with white light, the abatement was 99.9997%.

The photodynamic inactivation of Staphylococcus aureus in water using visible light with a new expanded porphyrin.

ROSSI, Giada;GOI, Daniele;COMUZZI, Clara
2012

Abstract

In this work, the results of the application of organic expanded porphyrins in the disinfection of water by the photodynamic inactivation (PDI) technique are presented. The photoinactivation properties of a novel, expanded porphyrin, namely 20-(4-carboxyphenyl)-2,13-dimethyl-3,12-diethyl-(22π) pentaphyrin (PCCox), were tested in the disinfection of water using Staphylococcus aureus as a Gram-positive bacteria model. The data showed that PCCox was effective against S. aureus bacteria at nanomolar concentrations. The variation with irradiation time and concentration was studied using both a multi-LED monochromatic light (λ ¼ 470 nm) and an incandescent light bulb with a wide emission spectrum. A PCCox dosage of 5 μM was sufficient to achieve a 99.997% abatement of S. aureus within 1 h of 40 W/m2 irradiation with monochromatic light (λ ¼ 470 nm), whereas under the same conditions using irradiation with white light, the abatement was 99.9997%.
File in questo prodotto:
File Dimensione Formato  
JWH2012.pdf

non disponibili

Tipologia: Altro materiale allegato
Licenza: Non pubblico
Dimensione 263.62 kB
Formato Adobe PDF
263.62 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11390/882216
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 18
  • ???jsp.display-item.citation.isi??? 17
social impact