While recent genome wide association studies have suggested novel low-grade glioma (LGG) stratification models based on a molecular classification, we explored the potential clinical utility of patient-derived cells. Specifically, we assayed glioma-associated stem cells (GASC) that are patient-derived stem cells representative of the glioma microenvironment.

A NF-κB signature predicts low-grade glioma prognosis: a precision medicine approach based on patient-derived stem cells

Ruaro, Maria Elisabetta;Isola, Miriam;Sorrentino, Marisa;Bourkoula, Evgenia;Manini, Ivana;Mangoni, Damiano;Toffoletto, Barbara;Caponnetto, Federica;Zanello, Andrea;Mariuzzi, Laura;Di Loreto, Carla;Beltrami, Antonio Paolo
;
Cesselli, Daniela
2017-01-01

Abstract

While recent genome wide association studies have suggested novel low-grade glioma (LGG) stratification models based on a molecular classification, we explored the potential clinical utility of patient-derived cells. Specifically, we assayed glioma-associated stem cells (GASC) that are patient-derived stem cells representative of the glioma microenvironment.
File in questo prodotto:
File Dimensione Formato  
1099582D-13A2-4825-ACBF-4D19904E7424.pdf

accesso aperto

Tipologia: Versione Editoriale (PDF)
Licenza: Creative commons
Dimensione 6.23 MB
Formato Adobe PDF
6.23 MB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11390/1126877
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 35
  • ???jsp.display-item.citation.isi??? 32
social impact