While recent genome wide association studies have suggested novel low-grade glioma (LGG) stratification models based on a molecular classification, we explored the potential clinical utility of patient-derived cells. Specifically, we assayed glioma-associated stem cells (GASC) that are patient-derived stem cells representative of the glioma microenvironment.

A NF-κB signature predicts low-grade glioma prognosis: a precision medicine approach based on patient-derived stem cells

Ruaro, Maria Elisabetta;Isola, Miriam;Sorrentino, Marisa;Bourkoula, Evgenia;Manini, Ivana;Mangoni, Damiano;Toffoletto, Barbara;Caponnetto, Federica;Zanello, Andrea;Mariuzzi, Laura;Di Loreto, Carla;Beltrami, Antonio Paolo
;
Cesselli, Daniela
2017

Abstract

While recent genome wide association studies have suggested novel low-grade glioma (LGG) stratification models based on a molecular classification, we explored the potential clinical utility of patient-derived cells. Specifically, we assayed glioma-associated stem cells (GASC) that are patient-derived stem cells representative of the glioma microenvironment.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11390/1126877
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